Tethered Fluorophore Motion: Studying Large DNA Conformational Changes by Single-fluorophore Imaging
نویسندگان
چکیده
منابع مشابه
Tethered fluorophore motion: studying large DNA conformational changes by single-fluorophore imaging.
We have previously introduced tethered fluorophore motion (TFM), a single-molecule fluorescence technique that monitors the effective length of a biopolymer such as DNA. TFM uses the same principles as tethered particle motion (TPM) but employs a single fluorophore in place of the bead, allowing TFM to be combined with existing fluorescence techniques on a standard fluorescence microscope. TFM ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2014
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2014.07.024